3 Best CBD Melatonin Capsules for Sleep: Reviews & Guide (April 2022)

By | last updated April 6, 2022

Medically reviewed by
Saira Zulfiqar, PharmD

Evidence Based 13

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Many people take melatonin-infused CBD products to relieve insomnia and improve their overall sleep quality.

But with such a wide variety of available products, it’s not always easy to make a choice. Many products contain less CBD than advertised, while others are simply too weak to produce the desired effect.

To make your search easier, we compared dozens of products based on third-party lab test results, hemp quality, potency, formula, customer reviews, price, and other criteria.

Read on for our reviews of the best CBD melatonin capsules for sleep.

CBD Terminology

  • Terpenes: aromatic plant compounds with a wide variety of beneficial properties (1).
  • Minor cannabinoids: CBN, CBG, and other beneficial cannabinoids found in smaller amounts than CBD. For hemp, THC also counts as a minor cannabinoid.
  • Hemp: non-intoxicating cannabis variety with high CBD and low THC levels (less than 0.3%).
  • Full-spectrum: whole-plant hemp extract containing multiple cannabinoids, terpenes, and flavonoids. This form of CBD is about 4 times more potent than pure CBD (2).
  • Broad-spectrum: whole-plant hemp extract similar to full-spectrum CBD, but with THC removed (may contain trace amounts).
  • CBD isolate: pure CBD with all other hemp compounds removed.

Lazarus Naturals Sleep+Melatonin Capsules (Best Overall)

lazarus naturals sleep melatonin capsules

Pros: 

  • Exceptionally low price
  • Full-spectrum CBD
  • Multi-ingredient sleep formula
  • Vertically integrated brand with USDA organic hemp
  • Comprehensive third-party testing

Cons:

  • None

Out of all the melatonin CBD capsules we reviewed, Lazarus Naturals’ sleep+melatonin capsules are the clear winner.

Their specialized sleep formula contains 30 mg full-spectrum CBD, 10 mg CBG, and 10 mg cannabinol (CBN), a minor cannabinoid touted to have sleep-promoting effects. There’s also 5 mg melatonin, plus the popular sleep herbs passionflower and lemon balm.

You can choose 10 or 40 capsules per pack. More importantly, these capsules cost only 2.5 to 4 cents per mg of cannabinoids. You’ll be hard-pressed to find such a low price for high-quality, third-party tested CBD capsules.

You can even get free shipping on orders over $75 and there’s a 60% discount program for low-income families and other qualifying individuals.

The employee-owned Lazarus Naturals is one of the most popular CBD brands on the market. It’s vertically integrated, meaning it controls every step of the production process, beginning with growing its own USDA-certified organic hemp in Central Oregon.

CbdMD CBD PM Softgel Capsules (Best THC-Free)

Pros: 

  • Multi-ingredient sleep formula
  • Comprehensive third-party testing
  • Organic Colorado & Kentucky hemp source

Cons:

  • Relatively low potency

If you’re looking for a THC-free option, cbdMD’s PM softgels are a great choice.

Each capsule contains 16.5 mg of broad-spectrum CBD, 3 mg of melatonin, and a blend of sleep-supporting herbs, including chamomile, valerian root, hops, lemon balm, and passionflower.

CbdMD’s PM CBD oil with this same formula won the 2020 consumer-voted “Product of the Year” award for the best CBD sleep aid.

You can choose between 30 or 60-capsule bottles with a price tag of $0.08-0.09 per mg of CBD, which is close to the price of regular CBD capsules.

CbdMD is a popular brand known for its THC-free* formulations. All of its products are comprehensively tested by a third-party lab and sourced from organic Colorado and Kentucky hemp.

*THC-free is defined as below the level of detection using valid scientific analytical tools.

Green Roads Sleep CBD Capsules (Best Reviews)

Pros: 

  • Hundreds of satisfied customer reviews
  • Organic Colorado hemp source
  • Comprehensive third-party testing

Cons:

  • Not a full-spectrum product

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The sleep capsules from Green Roads have the best customer feedback of any CBD melatonin capsules, with nearly 500 satisfied reviews.

They have a simple and effective formula made up of pure CBD (25 mg) and melatonin (5 mg), for a total of 30 capsules with 750 mg of CBD. As for price, you’ll pay about $0.07 per mg of CBD, which is slightly cheaper than average.

Founded in 2013, Florida’s Green Roads is one of the biggest and most trusted CBD brands in the country. Its products are sourced from organic Colorado hemp and tested by a third-party lab for potency and contaminants.

How We Choose CBD Melatonin Capsules

All of the products we recommend are chosen based on several criteria, including:

  • Third-party testing: these tests prove that CBD products contain correct levels of CBD and are free of contaminants.
  • Formula: we looked for capsules that contain CBD and melatonin and other ingredients that can aid sleep.
  • Hemp source: high-quality CBD products are made from organic hemp plants grown in the United States or Europe.
  • Reputation: reputable companies have many positive reviews and a strong reputation in the CBD industry.
  • Potency: we don’t recommend products that contain too little CBD to give you an effect.

How to Use

CBD melatonin capsules should be taken about 30-60 minutes before bed to give them time to start working. Generally speaking, CBD capsules will start to work within 30 minutes on an empty stomach, but up to an hour or longer if you ate recently (3).

Did you know? If your capsules contain powder, we highly recommend taking them alongside fat-containing foods, such as milk, cheese, eggs, or avocado. Research has shown that fats improve the oral bioavailability (fancy word for absorption) of CBD (4). You don’t need to do this if you’re using CBD softgels because they already contain fats.

Dosage

CBD affects everyone differently, so there’s no one universal dose that will work for everyone. It depends on your body weight, the severity of your sleeping problems, the kind of product you’re using, and other factors.

If you’re new to CBD, we recommend the expert-backed “start low and go slow” approach (5).

You should begin with a small dose (5-15 mg) and pay attention to the effects over the next two hours. If you don’t notice anything (CBD has fairly subtle effects), you can try gradually increasing the dosage over time until you start to feel the desired effects.

For example, you might take one capsule the first night, and if there’s no noticeable difference, try two capsules the next night.

As a general rule of thumb, most people take 20-50 mg doses of CBD. However, keep in mind that your capsules also contain melatonin and potentially other active ingredients, so you may need to take less CBD than usual to get an effect.

Safety and Side Effects

CBD has been extensively researched, showing that it’s a safe compound (6). Even the World Health Organization (WHO) concluded in its 2018 report that CBD is “generally well tolerated with a good safety profile.” (7)

While CBD can cause side effects, they’re usually mild and include: (8)

  • Feeling tired or drowsy
  • Dry mouth
  • Diarrhea
  • Low blood pressure
  • Lightheadedness

CBD can also potentially increase or decrease the effects of some prescription drugs.

However, most of CBD’s side effects were reported by studies using large oral doses of CBD isolate. This means regular CBD users are unlikely to experience them.

Still, we recommend checking with your doctor before taking CBD, especially if you already take prescription drugs.

Melatonin Safety

Melatonin is also considered a generally safe supplement. Its most common side effects are similar to CBD: headaches, dizziness, nausea, and drowsiness. Other rare side effects include mild anxiety, short-lasting feelings of depression, and confusion.

Melatonin can also interact with some medications, such as anticonvulsants.

Again, it’s best to consult your doctor before taking a product containing melatonin and CBD, particularly if you’re taking prescription medications.

CBD and Melatonin FAQs

Why Combine CBD with Melatonin?

If you’re looking to improve your sleep, combining CBD with melatonin is a no-brainer. Melatonin is arguably the most researched sleep aid out there, with strong evidence that it can help with insomnia, jet lag-related sleep problems, other sleep disorders, and support overall sleep quality (9, 10).

Does CBD Help with Sleep?

Although more research is needed, multiple studies have shown that CBD can support a healthy sleep cycle by reducing issues that lead to poor sleep quality, such as anxiety and pain (11, 12). Additionally, high doses of CBD (over 100 mg) can potentially make you sleepy directly, by working as a sedative (13).

References

  1. Russo, Ethan B. “Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects.” British journal of pharmacology 163.7 (2011): 1344-1364.
  2. Pamplona, Fabricio A., Lorenzo Rolim da Silva, and Ana Carolina Coan. “Potential clinical benefits of CBD-rich cannabis extracts over purified CBD in treatment-resistant epilepsy: observational data meta-analysis.” Frontiers in neurology 9 (2018): 759.
  3. Borodovsky, Jacob T., et al. “Smoking, vaping, eating: Is legalization impacting the way people use cannabis?.” International Journal of Drug Policy 36 (2016): 141-147.
  4. Birnbaum, Angela K., et al. “Food effect on pharmacokinetics of cannabidiol oral capsules in adult patients with refractory epilepsy.” Epilepsia 60.8 (2019): 1586-1592.
  5. Lucas, Catherine J., Peter Galettis, and Jennifer Schneider. “The pharmacokinetics and the pharmacodynamics of cannabinoids.” British journal of clinical pharmacology 84.11 (2018): 2477-2482.
  6. Bergamaschi, M. M., R. H. Queiroz, and A. W. Zuardi. “en Crippa, JA (2011). Safety and Side Effects of Cannabidiol, a Cannabis sativa Constituent.” Current Drug Safety 6.4: 237-249.
  7. WHO. Cannabidiol (CBD) Critical Review Report. June 7, 2018.
  8. Huestis, Marilyn A., et al. “Cannabidiol adverse effects and toxicity.” Current neuropharmacology 17.10 (2019): 974-989.
  9. Auld, Fiona, et al. “Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders.” Sleep Medicine Reviews 34 (2017): 10-22.
  10. Costello, Rebecca B., et al. “The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature.” Nutrition journal 13.1 (2014): 1-17.
  11. Shannon, Scott, et al. “Cannabidiol in anxiety and sleep: a large case series.” The Permanente Journal 23 (2019).
  12. Capano, Alex, Richard Weaver, and Elisa Burkman. “Evaluation of the effects of CBD hemp extract on opioid use and quality of life indicators in chronic pain patients: a prospective cohort study.” Postgraduate Medicine 132.1 (2020): 56-61.
  13. Babson, Kimberly A., James Sottile, and Danielle Morabito. “Cannabis, cannabinoids, and sleep: a review of the literature.” Current psychiatry reports 19.4 (2017): 1-12.

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