The Best High-Potency CBD Oil Products — Reviews and Buying Guide

Article by: , last updated September 13, 2020


Potency is one of the most important factors to consider when buying CBD oil. Most CBD tinctures on the market have a potency ranging between 10 mg and 30 mg per ml, which is considered low-to-medium. 

While this is enough for most people, there are many who prefer to use high-strength products due to a chronic health condition or some other reason.

It’s not easy to find a proper high-potency tincture, especially if you want it to be effective and affordable at the same time.

That’s why we researched and compared various brands to find the most potent, affordable, high-quality CBD oils. All of our choices come from reputable companies that post third-party lab test results and have thousands of satisfied customer reviews.

Here are our top picks for the best high-potency CBD oil products currently available and a buying guide to help you choose the right product. 

CBD Terminology

  • Hemp: a legal variety of cannabis with low THC levels (0.3% or less).
  • Full-spectrum: A whole-plant extract containing CBD, THC, and all other beneficial hemp cannabinoids and terpenes. This is considered the most effective form of CBD.
  • Broad-spectrum: A whole-plant hemp extract similar to full-spectrum, but with THC removed.
  • CBD isolate: Pure CBD with all other hemp compounds removed.

The Best High-Potency CBD Oils Reviewed

Highest Potency — cbdMD CBD Oil Tincture

If you’re looking for the absolute highest-potency CBD oils available, we recommend cbdMD. Its tinctures are easily the strongest options available, with potencies going as high as 100 mg, 167 mg, and even 250 mg per ml.

That’s enough for people with even the highest CBD dosage preferences. These third-party tested CBD oils are made with broad-spectrum CBD, which is free of THC but provides all of hemp’s beneficial cannabinoids and terpenes. 

They’re sold in 30 and 60 ml bottles with 300–7500 mg of CBD in total and come in four flavors: natural (unflavored), berry, orange, and mint.

CbdMD’s high-potency CBD oils are sourced from organic hemp grown in Kentucky and Colorado. They cost $0.05 per mg of CBD, which is much cheaper than the average market price for tinctures. 


  • Highest potency on the market
  • THC-free
  • Great price ($0.05–0.10 per mg)
  • Third-party testing
  • High-quality Colorado/Kentucky hemp source
  • Four flavors
  • Free shipping


  • Lacks third-party contaminant testing

Best Value — Lazarus Naturals High Potency CBD Tincture

If you want to get the best value, we always recommend Lazarus Naturals. This Oregon-based, employee-owned CBD company offers arguably the best combination of price and quality on the market. 

Its high potency CBD oil costs only $0.02–0.03 per mg of CBD, one of the lowest prices you’ll find anywhere. Lazarus Naturals also offers an unprecedented 60% discount to veterans, low-income families, and people with disabilities. 

This CBD oil has a potency of 50 mg per ml and comes in 15–120 ml bottles providing 750–6000 mg of CBD total. It’s available in both full-spectrum and CBD isolate formulas and multiple flavors. 

Most of the hemp used to make Lazarus Naturals’ products comes from the company’s own farm in central Oregon.


  • Excellent value ($0.02–0.03 per mg)
  • High potency
  • Full-spectrum and CBD isolate variations
  • Multiple flavors
  • Extensive third-party testing
  • High-quality Oregon hemp source
  • Free shipping


  • Lacks potencies above 50 mg/ml

Best Full Spectrum — CBDistillery CBD Oil Tincture

Full-spectrum CBD is the most effective type of CBD extract because it provides all of the cannabinoids, terpenes, and other beneficial compounds found in hemp.

Our top pick for high-potency, full-spectrum CBD oil is CBDistillery. This Colorado-based brand is one of the most popular choices thanks to its affordability and transparency.

CBDistillery’s third-party tested CBD oil is available in potencies as high as 83 mg and 167 mg per ml. It’s sold in 30 ml bottles with a total of 250–5000 mg CBD.

CBDistillery is one of the few companies with U.S. Hemp Authority Certification, a program that highlights compliance with leading hemp manufacturing standards. It sources CBD from organic, non-GMO hemp grown in Colorado.

These high-potency tinctures cost only $0.05 per mg of CBD. Relative to other CBD oils on the market, this price is considered far below average.


  • Full-spectrum, broad-spectrum, CBD isolate options
  • Very high potencies available
  • Great price ($0.05 per mg)
  • High-quality Colorado hemp source
  • Third-party testing
  • U.S. Hemp Authority Certification


  • Lacks third-party contaminant testing
  • No flavored options

Best Broad-Spectrum — Green Roads CBD Oil

Broad-spectrum CBD provides all of the beneficial compounds in hemp minus THC. Our top pick for high-potency broad-spectrum CBD oil is Green Roads, one of the biggest and most transparent brands out there.

It’s available in a high potency of 50 mg/ml, which will work great for people who want all the benefits of a whole-plant product without THC. This tincture comes in a 30 ml bottle with a total of 1500 mg of CBD sourced from organic hemp grown in Colorado. 

Unlike most CBD oils, Green Roads uses a unique measuring tool to dispense its oil instead of a dropper. This third-party tested tincture costs $0.10 per mg of CBD. This price is cheaper than the market average for CBD oil.


  • Whole-plant, THC-free formula
  • High-quality Colorado hemp source
  • Extensive third-party testing
  • Affordable price ($0.10 per mg)


  • Only one high-potency option
  • Not as cheap as many other leading brands

Best CBD Isolate — Medterra CBD Oil Tincture

CBD isolate is a pure form of CBD without any THC. Our top recommendation for CBD isolate tinctures is Medterra. 

The company’s highest-strength CBD tincture has a potency of 100 mg/ml, providing 3000 mg of CBD in each 30 ml bottle. 

This third-party tested tincture is sourced from organic hemp grown in Kentucky. It comes with an excellent price of $0.04 per mg of CBD, which is much lower than most competitor products.

Medterra is one of the most popular American CBD brands. It’s certified by the U.S. Hemp Authority, a program that highlights high hemp manufacturing quality standards.


  • Excellent price ($0.04 per mg)
  • 99.6% pure CBD isolate
  • High-quality Kentucky hemp source
  • Comprehensive third-party testing
  • U.S. Hemp Authority-certified


  • No flavored options

Best Reputation — NuLeaf Naturals CBD Oil

If you’re looking for potent CBD oil from a brand you can trust, we highly recommend Colorado’s NuLeaf Naturals. One of the oldest CBD brands in the U.S., NuLeaf is unique for only selling CBD oil and no other type of product like capsules or edibles.

Its tincture has a high potency of 60 mg per ml and comes in volumes ranging from 5 to 100 ml, adding up to 300–6000 mg of CBD in total.

Sourced from the highest quality organic hemp cultivated in Colorado, this third-party tested CBD oil contains full-spectrum CBD dissolved in USDA certified organic hemp seed oil.

Depending on the size you choose, NuLeaf Naturals’ CBD oil costs $0.07–0.13 per mg, a reasonable price to pay for the company’s strong reputation and high quality.


  • Full-spectrum hemp formula
  • Contains USDA certified organic hemp seed oil
  • Reasonable prices ($0.07–0.13 per mg)
  • Extensive third-party testing
  • High-quality Colorado hemp source
  • Free shipping


  • Average price ($0.13 average per mg CBD)
  • No flavored options
  • Only one potency

Best Concentrate — Endoca Hemp Oil Extract

CBD concentrates are ideal for people who require extremely high doses of CBD in an easy-to-use form. They’re also known as pastes due to their thick consistency.

If you’re looking for a high-potency CBD concentrate, our top choice is Denmark’s Endoca, one of the pioneers of the CBD industry. 

Its hemp oil extract comes in two extremely high potencies: 200 mg and 300 mg/ml, making it one of the strongest CBD products currently available. 

Sold in a 10 ml syringe with a total of 2000–3000 mg of full-spectrum CBD, this product is also available in a raw formulation with high amounts of CBDa, the precursor (parent molecule) to CBD.

 It’s sourced from organic Danish hemp and tested both in-house and by a third-party lab.

Endoca’s hemp oil extract costs €0.09 per mg of CBD, a reasonable, below-average price for a premium-grade CBD concentrate.


  • Very high potencies
  • Full-spectrum formula
  • High-quality Danish hemp source
  • Extensive third-party and in-house testing
  • Affordable price (€0.09 per mg)


  • None

Best Raw Tincture — Endoca Raw CBD Oil

Raw CBD oil is a special, unprocessed type of whole-plant hemp extract. If you prefer CBD oil in the most natural form possible, this is the ideal product for you.

Our top choice for high-potency, raw CBD oil is Endoca, one of the oldest and most experienced CBD brands in the world. 

Its raw CBD oil is available in a very high potency of 150 mg/ml, with a total of 1500 mg of CBD+CBDa in each 10 ml bottle.

Third-party tests confirm that it contains the full spectrum of hemp cannabinoids and terpenes, as well as high levels of CBDa, CBD’s parent molecule.

This tincture is derived from organic hemp grown by Endoca in Denmark. It costs €0.08 per mg of CBD, which is cheaper than the average market price for raw CBD tinctures. 


  • Very high potency
  • Full-spectrum, CBDa-rich hemp formula
  • High-quality Danish hemp source
  • Extensive third-party and in-house testing
  • Reasonable price (€0.08 per mg)


  • No flavored options

Best Flavors — Fab CBD Oil

If you’re after the best-tasting CBD oil, you won’t be disappointed by Fab CBD. The company offers high-potency CBD tinctures in five pleasant flavors: natural (unflavored), mint, vanilla, berry, and citrus.

These third-party tested full-spectrum CBD oils come in multiple strengths, with the most potent one providing 80 mg of CBD per ml for a total of 2400 mg of CBD in each 30 ml bottle.

They’re sourced from organic, non-GMO hemp grown in Colorado. The most potent version of Fab CBD’s oil costs $0.05 per mg — significantly cheaper than the market average for CBD tinctures.


  • Five flavor options
  • Full-spectrum hemp formula
  • Great price ($0.05 per mg)
  • High-quality Colorado hemp source
  • Comprehensive third-party testing


  • Only one high potency option

Best High-Potency Capsules — Lazarus Naturals Cycling Frog CBD Softgels

If you’re looking for high-potency CBD oil capsules, the cycling frog softgels from Lazarus Naturals are our top pick. 

These gelatin softgel capsules contain 100 mg of full-spectrum CBD, one of the highest potencies you’ll find. In comparison, most CBD capsules on the market max out at about 50 mg.

Lazarus Naturals’ third-party tested softgels are sourced from organic hemp grown in Oregon. They come in glass bottles of 4 or 20 capsules.

Lazarus Naturals cycling frog CBD softgels cost only $0.03–0.04 per mg of CBD. That’s much cheaper than the average for CBD capsules, especially considering the company’s excellent reputation.


  • Very high potency (100 mg)
  • Full-spectrum hemp formula
  • Excellent value ($0.03–0.04 per mg)
  • Extensive third-party testing
  • High-quality Oregon hemp source
  • Free shipping


  • Lacks variants with 30 or more capsules

Best High-Potency Gummies — cbdMD CBD Gummies

Potent CBD gummies are notoriously difficult to find. The popular brand cbdMD is one of the only companies that offers gummies with a relatively potency of 25 mg.

These gummies come with a tropical mix flavor and contain pure, THC-free CBD isolate. They’re made with organic, vegan-friendly ingredients and natural flavoring. Each bottle provides 30 gummies.

CbdMD’s gummies cost $0.09 per mg of CBD, which is cheaper than the market average for CBD gummies. They’re tested by a third-party lab to verify their potency and come from organic hemp cultivated in Kentucky and Colorado. 


  • High potency (50 mg)
  • Vegan-friendly (no gelatin)
  • Great price ($0.09 average per mg)
  • Third-party testing 
  • High-quality American hemp
  • Free shipping


  • No third-party tests for contaminants

Best High-Potency Vape Juice — CBDfx CBD Oil Vape Additive

If you’re looking for a potent CBD vape e-liquid, we recommend CBDfx. This popular CBD brand is best known for its vaping products. 

CBDfx’s CBD oil vape additive has a high-potency version providing 50 mg of CBD per ml.

And unlike most CBD juices on the market, this one is made with full-spectrum CBD, so you’re getting the complete benefits of hemp. 

CBDfx’s vape additive comes in a 10 ml bottle with a standard mix of vegetable glycerin (VG) and propylene glycol (PG) and 500 mg of CBD total. It’s derived from organic hemp grown in Kentucky and comprehensively tested by a third-party lab.

As for the price, CBDfx’s CBD oilvape additive costs $0.15 per mg of CBD, which is a great price point for a full-spectrum vape juice.


  • Full-spectrum hemp formula
  • High-quality Kentucky hemp source
  • Comprehensive third-party testing
  • Reasonable price ($0.15 per mg)


  • Lacks higher potencies

Best High-Potency Topical — Lazarus Naturals CBD Balm

Lazarus Naturals is a popular, employee-owned brand known for its unbeatable combination of great prices and high quality.

Its CBD balm has a potency of 20 mg/ml, one of the highest you’ll find in any topical CBD product. In comparison, most topicals contain only 0.5–10 mg of CBD per ml.

Better yet, this balm contains full-spectrum CBD, which means you’re getting all of hemp’s beneficial compounds.

The balm comes in 0.5 oz and 2 oz sizes containing 300–1200 mg of CBD in total and has five scent options: unscented, Portland rose, lavender, cedar citrus, and soothing mint.

It’s sourced from organic hemp grown in Oregon, most of which comes from Lazarus Naturals’ farm.

As for price, this potent CBD balm costs only $0.04 per mg of CBD, one of the lowest price points on the market. 


  • High potency (20 mg/ml)
  • Excellent price ($0.04 per mg)
  • Extensive third-party testing
  • High-quality, company-operated Oregon hemp source
  • Extensive third-party testing
  • Free shipping


  • None

High-Potency CBD Oil Buying Guide

Interested in buying high-potency CBD products but not sure where to start? We’ve put together this guide to answer the most common questions.

How Does CBD Strength Work?

CBD strength, also known as potency, refers to the concentration of CBD in a product. It’s usually expressed in milligrams (mg) of CBD per milligram (ml) of oil.

For example, a tincture that contains 1000 mg of CBD in a 30 ml bottle has a potency of 1000/30 = 33.33 mg/ml. If you take the same 30 ml bottle but with 2000 mg of CBD, it would have double the potency: 2000/30 = 66.67 mg/ml. 

The second option is much stronger, which also means you’d only need to take half the amount to achieve the same dose. You can also apply this principle to other CBD products. For example, potency for capsules is simply the amount of CBD provided per capsule. 

CBD potency/strength is a big deal when it comes to CBD oil because it can mean the difference between experiencing relief from your issues and not noticing any effects at all.

What Counts As a High CBD Potency?

Generally speaking, CBD oil concentrations of 40+ mg per ml (or per capsule/gummy) are considered high. Some CBD oil or CBD concentrate products can provide as much as 250–300 mg of CBD per ml. 

Why Do People Use High-Potency CBD Oil?

The average CBD user takes 10–40 mg doses of CBD 1-2 times a day. However, this amount may not be enough for everyone.

Whether it’s because you’re suffering from severe symptoms, have a high tolerance to cannabinoids, or simply have an endocannabinoid system that’s less responsive, some people need to take higher doses of CBD to find relief. 

In that case, your best bet is to choose a high-potency CBD product. Having said that, your chosen method of administering CBD will also influence its effectiveness.

How You Take CBD Matters

Most people use CBD in the form of oil, but there are many other product options, including capsules, gummies, vape e-liquids, and topicals. Each of these products is absorbed by the body in a different way, which affects their effectiveness.

CBD is best absorbed through the sublingual (under-the-tongue) and inhaled (vaping) routes. 

On the other hand, oral products such as capsules,  gummies, and other edibles have notoriously low bioavailability, meaning only a small portion of what you ingest actually reaches the blood and has a beneficial effect (1). 

That’s because much of the CBD gets lost in the digestive tract and liver before it can be absorbed.

The Type Of CBD Extract Matters

There’s one other key factor that affects the effectiveness of a CBD oil — the type of CBD it contains. CBD extracts come in three main forms: isolate, full-spectrum, and broad-spectrum CBD.

CBD isolate is pure CBD with all other hemp compounds removed.

Full-spectrum CBD is a whole-plant extract containing all of the cannabinoids, terpenes, and other beneficial natural compounds found in hemp. 

All these compounds work together in synergy, making full-spectrum CBD products more effective than those made with pure CBD. Researchers gave this phenomenon the name “entourage effect” (2).

Broad-spectrum CBD is similar to full-spectrum but undergoes an additional step to remove almost all traces of THC. 

To illustrate what this means for potency, let’s compare two CBD oils with the same strength of 50 mg/ml. One of these oils contains CBD isolate, while the other is made with full-spectrum CBD. 

The full-spectrum version will have stronger effects because it contains additional compounds that not only synergize with CBD but also have benefits of their own. 

That’s why it’s important to not only look for a high-potency product but also consider how you’re using it and which type of CBD extract it contains.

How to Select the Right CBD Strength

If you’re looking for high-potency CBD oil, chances are you didn’t find relief from a regular-strength product. If you want to figure out exactly how much CBD you need to take to relieve your symptoms, start with the highest CBD dosage you took previously. 

If you don’t notice any effects, gradually increase the dosage over time until you start to notice a difference. Keep in mind that some people may need to take CBD oil for several days or even weeks before they notice a benefit.

How to Choose the Best High-Potency CBD Oil

There are some key factors to keep in mind if you want to find an effective, affordable, high-potency CBD oil or any other CBD product.

Look for Third-Party Tested Brands

Third-party tests are necessary to confirm the safety and potency of CBD products. They’re the only way to protect yourself from low-quality products with little to no CBD. 

Performed by an independent lab, these tests check whether a product contains as much CBD as advertised. They can also check for pesticides, heavy metals, and other contaminants.

These days, it’s expected for any serious brand to use third-party testing and post the test documents directly on its website. If these test results are not available, that’s a major red flag.

Check the Hemp Source

Since CBD is extracted from hemp, how and where this hemp is grown is also important. 

High-quality CBD products are made from organic hemp grown in Colorado, Kentucky, Oregon, or in European countries. 

You should only buy from transparent companies that clearly list where and how their hemp is grown on their website. It’s even better if the company grows its hemp directly or uses USDA-certified organic hemp (which is still difficult to find due to regulations).


  1. Mechoulam R, Parker LA, Gallily R. Cannabidiol: an overview of some pharmacological aspects. J Clin Pharmacol. 2002;42(S1):11S-19S. doi:10.1002/j.1552-4604.2002.tb05998.x
  2. Russo, Ethan B. “Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects.” British journal of pharmacology 163.7 (2011): 1344-1364.

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