Best CBD Creams & Topicals for Eczema

Article by: , last updated April 21, 2021

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CBD has rapidly grown into the leading health and wellness trend. Although it’s mostly used to deal with anxiety, pain, insomnia, more and more people are using CBD for skin conditions such as acne and eczema.

There’s growing evidence that CBD’s anti-inflammatory, antioxidant, and other beneficial properties can help with eczema. 

But with so many CBD products on the market, it can be difficult to choose the right one.

We reviewed dozens of brands to find the best CBD creams and other topical products for eczema. Read on for our picks and a research-backed guide to help you make an educated choice.

How We Choose Products

We choose CBD products based on relevant criteria, including:

  • Third-party testing: these tests prove that a CBD vape juice contains full-spectrum hemp extract, correct levels of CBD, and lacks contaminants.
  • Formula: For topical products, we consider the type of CBD used, as well as additional skincare ingredients.
  • Hemp source: high-quality CBD products are made from organic hemp grown in the United States or Europe.
  • Reputation: leading CBD companies have positive customer reviews and a strong reputation.
  • Potency: we don’t recommend products that contain too little CBD to give you an effect.

CBD Terminology

  • Terpenes: plant compounds with a wide variety of beneficial properties.
  • Minor cannabinoids: CBN, CBC, and other beneficial cannabinoids that are present in smaller amounts than CBD.
  • Hemp: a non-intoxicating variety of cannabis with low THC levels (0.3% or less).
  • Full-spectrum: whole-plant hemp extract containing CBD, THC, and other beneficial hemp cannabinoids and terpenes. This is considered the most effective form of CBD.
  • Broad-spectrum: whole-plant hemp extract similar to full-spectrum CBD, but with THC removed.
  • CBD isolate: pure CBD with all other hemp compounds removed.

The Best CBD Creams and Topicals for Eczema

CBDefine Skin Care Cream (Best Overall)


  • Full-spectrum hemp extract
  • Added ingredients that may help with eczema
  • Affordable price
  • Organic Colorado hemp source
  • Comprehensive third-party testing
  • U.S. Hemp Authority-certified


  • One potency option

The overall best CBD cream for eczema is offered by CBDistillery. This popular, reputable Colorado brand offers a full range of high-quality CBD products are affordable prices.

The company’s CBDefine cream comes in a 30 ml jar providing 500 mg of full-spectrum CBD. It’s formulated with all-natural skincare ingredients, including those that may help with eczema, such as tea tree oil and hemp seed oil.

Like all CBDistillery products, this cream is sourced from organic Colorado hemp and tested by a third-party lab to verify its potency and safety. 

The CBDefine skincare cream costs $0.10 per milligram (mg) of CBD. This price is considered lower than the average for CBD creams.

CBDistillery is also one of few brands with U.S. Hemp Authority Certification, which means it follows hemp industry best practices.

Lazarus Naturals CBD Lotion (Best Lotion and Value)


  • Excellent price
  • Three scent and size options
  • Extensive third-party testing
  • High-quality organic Oregon hemp source
  • Employee-owned company
  • Free shipping over $25


  • Fewer additional ingredients that can help with eczema

Our top recommendation to get the best bang for your buck is Lazarus Naturals. This ethical brand provides some of the lowest prices for high-quality CBD products.

This is the best CBD lotion for eczema and it costs only $0.04 per mg of CBD. Such low prices for CBD topicals are unheard of. Besides, Lazarus offers a massive 60% discount to veterans, people with disabilities, and low-income families.

Lazarus’ lotion contains full-spectrum CBD extract alongside other compounds that can relieve inflammation and provide other benefits, such as aloe vera leaf juice and jojoba seed oil.

It comes in three sizes, 300 mg (1 oz), 1000 mg (3.3 oz), or 2000 mg (6.7 oz) of CBD, as well as three scents: unscented, Pacific pine, and Portland rose.

Lazarus Naturals also offers a full-spectrum balm with the same per-mg price containing 400 or 1200 mg of CBD with similar ingredients but a higher potency (20 mg of CBD per ml). 

Lazarus Naturals is one of the most respected and experienced CBD brands. It’s an employee-owned company that grows most of its hemp in Central Oregon and provides extensive third-party lab test results for all products.

In comparison, most CBD companies purchase their hemp or finished extracts from other producers.

Endoca CBD Cream (Best Quality)


  • Added ingredients that may help with eczema
  • High-quality organic Danish hemp source
  • Extensive third-party and in-house testing
  • Affordable price


  • Some may prefer American-made products

If quality is your top concern, then the CBD cream from Endoca is a great option. Denmark’s Endoca is one of the most experienced, reputable CBD brands in the world.

This product is another serious contender for the best CBD cream for eczema.

It comes in a 100 ml jar containing either 450 mg or 1500 mg of full-spectrum CBD blended with shea butter, vitamin E, coconut oil, and other natural ingredients that can help with eczema by moisturizing the skin, reducing itching, and providing other benefits.

Endoca’s cream costs €0.04 per mg of CBD. As far as topical CBD products go, this affordable price is considered well below average.

Unlike most CBD companies, Endoca controls the entire process from seed to shelf and tests at every step — growing, harvesting, extracting, and the finished product. 

The company grows its organic hemp in Denmark in partnership with local farmers and has its products tested by a third-party lab.

CBDfx Calming CBD Balm Stick (Best Salve)


  • Added ingredients that may help with eczema
  • Excellent price
  • Organic Kentucky hemp source
  • Extensive third-party testing


  • Not a full-spectrum CBD product

Balms and salves are a great choice for people who prefer simple, water-free topical products. One of the best CBD salves for eczema is offered by CBDfx.

This popular California-based brand is known for its expertly formulated CBD products ranging from tinctures to vape e-liquids. Its calming balm is specifically designed to soothe sensitive skin without being irritating. 

Each 60 ml stick contains 750 mg or 3000 mg of pure CBD isolate blended with other, all-natural skincare ingredients that can moisturize, reduce inflammation, and help with other eczema symptoms, including tea tree oil, lavender, and chamomile.

Derived from organic Kentucky hemp, this balm is comprehensively tested by a third-party lab to confirm that it’s safe and potent. CBDfx’s calming balm has a per-mg price of $0.03-0.05, which is incredibly low.

Kiara Naturals CBD Blue Magic Cream (Best Formula)



  • Anti-eczema herbal formula
  • High potency
  • Swiss hemp source
  • Third-party testing


  • Not a full-spectrum CBD product
  • Lacks third-party contaminant tests

If you’re looking for a formula that’s specifically designed for eczema and related inflammatory skin concerns, we recommend the blue magic cream from Kiara Naturals.

It carries 1000 mg of pure CBD and CBG in a 30 ml container, giving it a high potency of 33 mg/ml.

More importantly, it contains seven botanical ingredients that can help with eczema, inflammation, and skin repair: aloe vera, gotu kola, indigofera, Chinese goldthread, Chinese skullcap, stellaria, and vitamin E.

This third-party tested cream costs $0.09 per mg of CBD, which is quite good since you’re getting so many added ingredients.

Kiara Naturals is a Swiss brand known for offering CBD products infused with popular medicinal herbs.

CBDMEDIC Eczema Therapy Ointment (Best Specialized Topical)


  • Anti-eczema formula
  • Whole-plant hemp extract
  • Organic American hemp source
  • Third-party tested


  • Low CBD strength

The eczema therapy medicated ointment from CBDMEDIC is one of the only CBD topicals designed specifically for eczema. It contains 1% colloidal oatmeal, a popular natural ingredient that can help reduce itching, dryness, and other symptoms of eczema.

Aside from that, the ingredients list includes 200 mg of broad-spectrum CBD and other compounds that may be helpful for eczema, including tea tree oil, jojoba seed oil, zinc, and beeswax.

This third-party tested, 40-gram ointment is derived from organic hemp cultivated in Colorado and Oregon. With a cost of $0.15 per mg of CBD, this product is close to average price point for CBD topicals. However, you’re still getting a good deal because of its unique formulation.

PlusCBD Gold Formula CBD Balm (Best Travel-Size)


  • Full-spectrum hemp extract
  • Added ingredients that may help with eczema
  • Organic European hemp source
  • Comprehensive in-house and third-party testing
  • U.S. Hemp Authority-certified


  • Relatively expensive

The travel-size hemp balm from PlusCBD oil is a great choice if you’re looking for a product you can take with you and use on the go. 

This travel-sized balm comes in a 0.42 oz stick with 45 mg of full-spectrum CBD alongside multiple ingredients that may be beneficial for inflammation, itching, and dryness, including sweet almond oil, white willow bark, and tocopherol (vitamin E).

It’s sourced from organic European hemp and costs $0.33 per mg of CBD. This price is higher than average for CBD topicals, but still reasonable given PlusCBD’s premium-level product quality. 

PlusCBD was one of the first American CBD companies and continues to be popular today. It tests all of its products in-house and through a third-party lab. 

PlusCBD is also unique for being one of the only CBD brands to hold both self-affirmed Generally Recognized as Safe (GRAS) status and U.S. Hemp Authority Certification, two rigorous safety and quality compliance programs.

How to Choose the Best CBD Product

Here are some helpful tips to help you choose the ideal CBD product for eczema.

Look for Third-Party Tested Brands

Third-party testing is the best way to confirm the efficacy and safety of CBD products. These tests are done by an independent laboratory that checks whether a given product carries as much CBD as it says on the label. 

Third-party tests can also look for the presence of pesticides, heavy metals, and other contaminants.

In this day and age, all reputable CBD companies utilize third-party testing and share the test results publicly on their websites. Lack of these tests is a big red flag. 

Check the Hemp Source

CBD comes from hemp, which means the plant quality and cultivation process used matters. The best hemp is organic and grown in one of three states: Colorado, Kentucky, and Oregon. 

European countries are also an excellent source of hemp because many have been growing it continuously for centuries. 

Check the company website for this information. Bonus points if the company is USDA-organic certified or grows its own hemp.

Choose Your CBD Extract

As we highlighted at the beginning of the article, there are three main types of CBD: isolate, full spectrum, and broad spectrum. 

If you want to get the best effects out of a CBD product for eczema or any other health issues, it’s best to use a full-spectrum or broad-spectrum product. 

That’s because they benefit from the cannabis “entourage effect” — the combined effects of all cannabis compounds working together in synergy instead of pure CBD on its lonesome (1). 

CBD Dosage for Eczema

There isn’t enough evidence to recommend a specific dose of CBD that’s ideal for eczema. Besides, the ideal dose varies from person to person based on the severity of your symptoms, the type of product you’re using, and other factors.

The best thing you can do is look for a product that has a potency of at least 4 mg of CBD per ml to make sure that it’s strong enough to have an effect on your skin. Anything less than that runs the risk of being too weak to provide a benefit. 

Safety and Side Effects

CBD is already an incredibly safe, non-intoxicating substance that’s only been associated with minor side effects (2).

However, topical products infused with CBD are even safer because cannabidiol has a hard time penetrating into your skin and reaching the bloodstream. Since CBD can’t reach the blood, that means it can’t even cause any side effects.

Nonetheless, you should be aware that your skin can react negatively to other ingredients in a topical CBD product. 

Guide to Using CBD for Eczema

Interested in trying out CBD for eczema but not sure where to start? Here’s our evidence-based buying guide to using CBD for this common skin condition.

What is CBD?

Cannabidiol (CBD) is a natural cannabinoid compound that comes from cannabis. Thanks to its non-intoxicating properties and multiple health benefits, CBD has grown widely popular in the past several years.

CBD is typically sourced from hemp, which is a type of cannabis with high cannabidiol but low THC levels (0.3% or less).

Most people use it in the form of CBD oil, a liquid tincture where the CBD is dissolved in a carrier oil to aid its absorption and applied under the tongue. However, CBD can also be used in many other products, including topicals such as creams, salves, lotions, and balms.

What is Eczema?

Also known as atopic dermatitis, eczema is a condition characterized by red, itchy, and inflamed skin. Eczema tends to last a long time and with ongoing flare-ups. It’s estimated to affect up to 20% of children and 3% of adults worldwide (3).

Health experts believe this condition is linked to immune system dysfunction & allergies, stress, as well as other factors that can disrupt the skin’s barrier, which protects you from external threats and seals in moisture. 

Eczema is not curable, and therapy usually focuses on soothing and preventing the flare-ups. 

CBD Benefits for Eczema

CBD may help relieve the inflammation that characterizes eczema, which in turn can alleviate symptoms such as itching, redness, and dryness.

One promising Italian study tested the effects of a CBD-infused ointment on people with psoriasis, eczema, and scarring related to these conditions. 

The study participants used the ointment daily for 90 days, experiencing an improvement of skin hydration, elasticity, and other measures of skin health, as well as reduced scarring and blemishes (4).

CBD can also help eczema sufferers indirectly through its beneficial effects on mood, anxiety, and sleep, as issues with these are more common in people suffering from eczema and may also worsen its symptoms. (5, 6, 7, 8).

Did you know? Adding hemp seed oil to your diet — the oil pressed out of hemp seeds, not the same thing as CBD oil — may also help with eczema. In one study, people who used dietary hemp seed oil saw improvements in eczema symptoms, whereas those who were taking olive oil had no improvement (9). 

How Does CBD Help with Eczema?

Researchers believe CBD can have a positive effect on eczema by interacting with the body’s endocannabinoid system (ECS). 

This system is composed of three parts: cannabinoid receptors, endocannabinoids (cannabinoids that your body makes), and special enzymes that build and break them down.

The major role of the ECS is to maintain homeostasis, a healthy state of balance throughout the whole body. As part of its job, the ECS plays an important role in the health of your skin by controlling inflammation, cell growth, and other crucial processes (10).

Researchers theorize that ECS dysfunction could even be at the core of many health disorders, including eczema (11).

CBD can support the ECS by suppressing the enzyme that breaks down anandamide, one of the main endocannabinoids made in the body (12). 

Anandamide has been demonstrated to reduce skin inflammation and itching, highlighting the involvement of the ECS in healthy skin function (13).

Also, test-tube studies have shown that CBD can help regulate the dysfunctional immune system responses that may play a role in eczema (14). This isn’t surprising as the ECS is also known to regulate immune system function (15).

Other Helpful Topical Ingredients for Eczema

If you want to use a CBD-infused topical product for eczema, it’s helpful to look for one that contains some of the following ingredients:

  • Vitamin E: also known as tocopherol, this vitamin has been demonstrated to improve itching, eczema extent, and other measures of eczema severity in research studies (16).
  • Colloidal oatmeal: a review of multiple studies found that products containing colloidal oatmeal improved itching, dryness, eczema severity, and overall quality of life in eczema sufferers (17).
  • Emollients/moisturizers: Moisturizing the skin is one of the best approaches to eczema because it helps protect the damaged skin barrier and keep in moisture. Some studies have shown that emollients are beneficial for eczema (18).

Other natural ingredients listed below may also be beneficial for some people with eczema. However, their effects are more variable and don’t have as much research evidence:

  • Tea tree oil: there are some anecdotal reports of tea tree oil helping with eczema, although it doesn’t seem to work for everyone. There’s also evidence that it may reduce skin inflammation caused by histamine, which may play a role in eczema (19).
  • Coconut oil: some people with eczema swear by the benefits of coconut oil, while others find that it only makes things worse. In any case, there’s evidence that coconut oil can reduce skin inflammation and enhance barrier function, both of which are beneficial for eczema (20).
  • Aloe vera: this popular plant is proposed to have antibacterial, wound healing, and immunity-modulating properties (21). However, there’s a lack of evidence for its benefits specifically in eczema.

How To Apply CBD Topicals for Eczema

You can apply a topical CBD product directly to the area of skin affected by eczema. It’s best to clean and dry the area first and then massage the product into your skin as you would with most regular topicals.

You can start with a small amount and see if that provides you with some relief. If that’s not enough, you can always apply more later.

Can Topical CBD Cause a Failed Drug Test for THC?

It’s highly unlikely that a topical CBD product will show up as a positive drug test for THC. Not only do CBD products contain very small THC amounts (less than 0.3%) but topically applied CBD has a hard time reaching the bloodstream. 

Can You Apply CBD Oil to Eczema?

Yes, you can apply standard CBD oil to eczema. Having said that, you’ll probably have better results from using a dedicated topical product since CBD oil tinctures are designed to be taken sublingually (under the tongue).

Topicals vs. Other CBD Products

Topical CBD products differ from CBD oil, capsules, and edibles in several important ways. For one, they’re applied to the skin instead of taken internally. Furthermore, their effects are only felt where you apply them, instead of the whole body. 

Topicals also can’t cause side effects because CBD typically can’t reach your bloodstream when applied to the skin. The effects of topical CBD last for at least a few hours.

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