Best CBD Creams & Topicals for Eczema: Reviews & Guide (Mar. 2022)

By | last updated May 10, 2022

Medically reviewed by
Saira Zulfiqar, PharmD

Evidence Based 23

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There’s growing evidence that CBD’s anti-inflammatory, antioxidant, and other beneficial properties can help with eczema. 

But with so many CBD topicals on the market, it can be difficult to choose the right one, especially with a reasonable price.

That’s why we compared dozens of topical products based on their formula, third-party test results, hemp quality, potency, customer reviews, price, and more.

Here are the best CBD creams & topicals for eczema.

Top 5 Best CBD Creams & Topicals for Eczema

  1. Best Overall: Medterra Manuka CBD cream | full review
  2. Best Lotion & Value: Lazarus Naturals CBD Lotion | full review
  3. Best Salve: CBDfx Calming Balm Stick | full review
  4. Designed for Eczema: CBDMEDIC Eczema Ointment | full review
  5. Best Formula: Kiara Naturals Dermacure Cream | full review

CBD Terminology

  • Terpenes: aromatic plant compounds with a wide variety of beneficial properties (1).
  • Minor cannabinoids: CBN, CBG, and other beneficial cannabinoids found in smaller amounts than CBD. For hemp, THC also counts as a minor cannabinoid.
  • Hemp: non-intoxicating cannabis variety with high CBD and low THC levels (less than 0.3%).
  • Full-spectrum: whole-plant hemp extract containing multiple cannabinoids, terpenes, and flavonoids. This form of CBD is about 4 times more potent than pure CBD (2).
  • Broad-spectrum: whole-plant hemp extract similar to full-spectrum CBD, but with THC removed (may contain trace amounts).
  • CBD isolate: pure CBD with all other hemp compounds removed.

Medterra Manuka Honey Healing Cream (Best Overall)

medterra manuka honey cbd cream

5/5

CBD Potency4.2 mg/ml
Volume30-60 ml
Total CBD125-250 mg
Cost per mg CBD$0.24-0.32
TypeIsolate 
Third-Party TestView report

Use coupon code CBDTHINKER for 15% off

Pros:

  • Contains manuka honey
  • Comprehensive third-party testing
  • U.S. Hemp Authority-certified

Cons:

  • Not a full-spectrum product

Medterra’s manuka honey healing cream comes in a 30 ml jar providing 125-250 mg of pure CBD. It’s formulated with manuka honey, which has been shown to reduce eczema in research studies, and has other ingredients that may help, such as tea coconut oil.

Like all Medterra products, this cream is sourced from organic Kentucky hemp and tested by a third-party lab to verify its potency and safety. It costs $0.24-0.32 per milligram (mg) of CBD, which is higher than average but still reasonable given the addition of manuka honey.

Medterra is a reputable brand offering a full range of high-quality CBD products at affordable prices. It’s one of few companies certified by the U.S. Hemp Authority, highlighting its adherence to strict hemp production standards.

Lazarus Naturals CBD Lotion (Best Lotion & Value)

lazarus naturals cbd lotion

5/5

CBD Potency20 mg/ml
Volume2.5 oz (75 ml)
Total CBD1500 mg
Cost per mg CBD$0.02
TypeFull-spectrum 
Third-Party TestView report

Pros:

  • Very cheap
  • Full-spectrum CBD
  • Extensive third-party testing
  • High-quality organic Oregon hemp source

Cons:

  • Lacks special ingredients for eczema

Our top recommendation to get the best bang for your buck is Lazarus Naturals. This is the best CBD lotion for eczema and it costs only $0.02 per mg of CBD. Such low prices for a high-quality CBD topical are unheard of.

Lazarus’ lotion contains 1500 mg of full-spectrum CBD alongside other compounds that can relieve inflammation, such as aloe vera leaf juice and jojoba seed oil.

It comes in two scents: unscented and Pacific pine. Lazarus Naturals also offers a full-spectrum balm with similar ingredients but a higher CBD potency (50 mg/g). 

An employee-owned company that grows its own hemp in Central Oregon, Lazarus Naturals is respected for its affordable, high-quality products. Most other CBD companies buy their hemp or extracts from other producers.

CBDfx Calming CBD Balm Stick (Best Salve)

cbdfx balm stick

5/5

CBD Potency12.5-50 mg/ml
Volume60 ml
Total CBD750-3000 mg
Cost per mg CBD$0.03-0.05
TypeBroad-spectrum 
Third-Party TestView report

Use coupon code TAKE15 for 15% off

Pros:

  • Added ingredients that can help with eczema
  • Excellent price
  • Extensive third-party testing

Cons:

  • Not a full-spectrum CBD product

Balms and salves are a great choice for people who prefer simple, water-free topical products. One of the best CBD salves for eczema is offered by CBDfx.

Each 60 ml stick contains 750 mg or 3000 mg of pure CBD isolate blended with all-natural skincare ingredients that can moisturize, reduce inflammation, and help with other eczema symptoms, including tea tree oil, lavender, and chamomile.

Derived from organic Kentucky hemp, this balm is comprehensively tested by a third-party lab. It costs $0.03-0.05 per mg of CBD, which is quite cheap.

California’s CBDfx is known for expertly formulated CBD products ranging from tinctures to gummies.

CBDMEDIC Eczema Ointment (Designed for Eczema)

cbdmedic eczema ointment

5/5

CBD Potency5 mg/g
Volume40 g
Total CBD200 mg
Cost per mg CBD$0.15
TypeBroad-spectrum 
Third-Party TestView report

Use coupon code CWEB10 for 10% off

Pros:

  • Designed specifically for eczema
  • Extensive third-party testing

Cons:

  • Need product batch number to view third-party test report

The eczema ointment from CBDMEDIC is one of the only CBD topicals designed specifically for eczema. It contains 1% colloidal oatmeal, a popular natural ingredient that can help reduce itching, dryness, and other symptoms of eczema.

Aside from that, the ingredients list includes 200 mg of broad-spectrum CBD and other compounds that may be helpful for eczema, including tea tree oil, jojoba seed oil, zinc, and beeswax.

This ointment is derived from organic hemp cultivated in Colorado and Oregon. With a cost of $0.15 per mg of CBD, it costs about average. But you’re still getting a good deal because of its unique formulation.

CBDMEDIC is owned by Charlotte’s Web, one of the oldest and most respected CBD brands in the world.

Kiara Naturals CBD Dermacure Cream (Best Formula)

kiara naturals dermacure cream

5/5

CBD/CBG Potency100 mg/ml
Volume30 ml
Total CBD/CBG3000 mg
Cost per mg$0.02
TypeIsolate
Third-Party TestView report

use coupon code KTC15 for 10% off

Pros:

  • Herbal anti-eczema & psoriasis formula
  • High potency
  • Third-party tested

Cons:

  • Lacks third-party contaminant tests
  • Need product batch number to view third-party test report

The CBD Dermacure cream from Kiara Naturals has the most impressive anti-eczema and psoriasis formula we’ve seen.

It combines 3000 mg of CBD and CBG with botanicals that can help with eczema, inflammation, and skin repair, including aloe vera, gotu kola, indigofera, Chinese goldthread, Chinese skullcap, stellaria, and vitamin E.

This third-party tested cream costs $0.02 per mg of cannabinoids, which is very cheap since you’re getting so many additional ingredients. Kiara Naturals is a Swiss brand known for offering CBD products infused with popular medicinal herbs.

How We Choose CBD Creams & Topicals

Here are the criteria we use to find the right CBD creams and topicals for eczema:

  • Third-party test results (to verify the CBD content and lack of contaminants)
  • Formula (we look for added ingredients that can help with eczema)
  • Type of CBD (to get the best effects)
  • Product potency (to avoid products with too little CBD)
  • Hemp quality (to get a high-quality product)
  • Company reputation (to verify the company can be trusted)
  • Price (to get a good deal)

Read on for a closer look at how we judge these factors. You can also use these tips to find the best CBD creams on your own.

Third-Party Testing

Third-party testing is the best way to confirm the efficacy and safety of CBD products. These tests are done by an independent laboratory that checks whether a given product carries as much CBD as it says on the label. 

Third-party tests can also look for the presence of pesticides, heavy metals, and other contaminants.

In this day and age, all reputable CBD companies utilize third-party testing and share the test results publicly on their websites. A lack of these tests is a big red flag. 

We check the test results for all the products we review to make sure they contain advertised levels of CBD, the correct type of CBD, and are free of contaminants. For full-spectrum products, we also check the concentrations of minor cannabinoids (and terpenes, if available).

Formula

We look for topical products that contain additional natural ingredients that can help with eczema, such as tea tree oil. Read more below about what kinds of ingredients you want to look for.

Hemp Quality

CBD comes from hemp, which means the plant quality and cultivation process used matters. The best American hemp is organic and grown in one of three states: Colorado, Kentucky, and Oregon. 

European countries are also an excellent source of hemp because many have been growing it continuously for centuries. 

Check the brand’s website for this information. It’s even better if the company uses USDA-certified organic ingredients or directly grows its hemp.

Type of CBD

As we highlighted at the beginning of the article, there are three main types of CBD: isolate, full-spectrum, and broad-spectrum. 

If you want to get the best effects out of a CBD product for eczema or any other health issues, it’s best to use a full-spectrum or broad-spectrum product. 

That’s because they benefit from the cannabis “entourage effect” — the combined effects of all cannabis compounds working together in synergy instead of pure CBD on its lonesome (1). 

Company Reputation

We also consider the reputation of CBD companies. The brands we recommend have overwhelmingly positive customer reviews that help verify that you’re getting effective CBD oil and good customer service.

They’re also transparent about their hemp source, third-party testing results, the people behind the company, and provide other helpful details to build trust with customers.

Price

CBD oil is not cheap, so we also consider the price. We look for products that are affordable yet of good quality. We also make it easy to tell if you’re paying a low, average, or high price by comparing the price per milligram (mg) of CBD. 

Generally speaking, topical CBD products fall into three tiers:

  1. Low: $0.10 or less per mg
  2. Average: $0.11-$0.25 per mg
  3. High: $0.26+ per mg

CBD Dosage for Eczema

There isn’t enough evidence to recommend a specific dose of CBD that’s ideal for eczema. Besides, the ideal dose varies from person to person based on the severity of your symptoms, the type of product you’re using, and other factors.

The best thing you can do is look for a product that has a potency of at least 4 mg of CBD per ml to make sure that it’s strong enough to have an effect on your skin. Anything less than that runs the risk of being too weak to provide a benefit. 

Safety and Side Effects

CBD is already a safe, non-intoxicating substance that’s only been associated with few and minor side effects (3).

Additionally, topical products infused with CBD are even safer because cannabidiol has a hard time penetrating into your skin and reaching the bloodstream. Since CBD can’t reach the blood, that means it can’t even cause any side effects.

Nonetheless, you should be aware that your skin can react negatively to other ingredients in a topical CBD product. 

Guide to Using CBD for Eczema

Interested in trying out CBD for eczema but not sure where to start? Here’s our evidence-based buying guide to using CBD for this common skin condition.

What is CBD?

Cannabidiol (CBD) is a natural cannabinoid compound that comes from cannabis. Thanks to its non-intoxicating properties and multiple health benefits, CBD has grown widely popular in the past several years.

CBD is typically sourced from hemp, which is a type of cannabis with high cannabidiol but low THC levels (0.3% or less).

Most people use it in the form of CBD oil, a liquid tincture where the CBD is dissolved in a carrier oil to aid its absorption and applied under the tongue. However, CBD can also be used in many other products, including topicals such as creams, salves, lotions, and balms.

What is Eczema?

Also known as atopic dermatitis, eczema is a condition characterized by red, itchy, and inflamed skin. Eczema tends to last a long time and with ongoing flare-ups. It’s estimated to affect 20% of children and up to 10% of adults in high-income countries (4).

Health experts believe this condition is linked to immune system dysfunction & allergies, stress, as well as other factors that can disrupt the skin’s barrier, which protects you from external threats and seals in moisture. 

Eczema is not curable, and therapy usually focuses on soothing and preventing flare-ups. 

CBD Benefits for Eczema

CBD may help relieve the inflammation that characterizes eczema, which in turn can alleviate symptoms such as itching, redness, and dryness.

One promising Italian study tested the effects of a CBD-infused ointment on people with psoriasis, eczema, and scarring related to these conditions. 

The study participants used the ointment daily for 90 days, experiencing an improvement of skin hydration, elasticity, and other measures of skin health, as well as reduced scarring and blemishes (5).

CBD can also help eczema sufferers indirectly through its beneficial effects on mood, anxiety, and sleep. Research suggests that these issues are more common in people suffering from eczema and may worsen its symptoms (6, 7, 8, 9).

Did you know? Adding hemp seed oil to your diet — the oil pressed out of hemp seeds, not the same thing as CBD oil — may also help with eczema. In one study, people who used dietary hemp seed oil saw improvements in eczema symptoms, whereas those who were taking olive oil had no improvement (10). 

How Does CBD Help with Eczema?

Researchers believe CBD can have a positive effect on eczema by interacting with the body’s endocannabinoid system (ECS). 

This system is composed of three parts: cannabinoid receptors, endocannabinoids (cannabinoids that your body makes), and special enzymes that build and break them down.

The major role of the ECS is to maintain homeostasis, a healthy state of balance throughout the whole body. As part of its job, the ECS plays an important role in the health of your skin by controlling inflammation, cell growth, and other crucial processes (11).

Researchers theorize that ECS dysfunction could even be at the core of many health disorders, including eczema (12).

CBD can support the ECS by suppressing the enzyme that breaks down anandamide, one of the main endocannabinoids made in the body (13). 

Anandamide has been demonstrated to reduce skin inflammation and itching, highlighting the involvement of the ECS in healthy skin function (14).

Also, test-tube studies have shown that CBD can help regulate the dysfunctional immune system responses that may play a role in eczema (15). This isn’t surprising as the ECS is also known to regulate immune system function (16).

Other Helpful Topical Ingredients for Eczema

If you want to use a CBD-infused topical product for eczema, it’s helpful to look for one that contains some of the following ingredients:

  • Vitamin E: also known as tocopherol, this vitamin has been demonstrated to improve itching, eczema extent, and other measures of eczema severity in research studies (17).
  • Colloidal oatmeal: a review of multiple studies found that products containing colloidal oatmeal improved itching, dryness, eczema severity, and overall quality of life in eczema sufferers (18).
  • Emollients/moisturizers: Moisturizing the skin is one of the best approaches to eczema because it helps protect the damaged skin barrier and keep in moisture. Some studies have shown that emollients are beneficial for eczema (19).
  • Manuka honey: this special type of honey comes from a shrub in New Zealand and has been shown to improve eczema in research studies (20)

Other natural ingredients listed below may also be beneficial for some people with eczema. However, their effects are more variable and don’t have as much research evidence:

  • Tea tree oil: there are some anecdotal reports of tea tree oil helping with eczema, although it doesn’t seem to work for everyone. One study found that tea tree oil improved contact dermatitis and had potential as an “anti-eczematic agent” (21).
  • Coconut oil: some people with eczema swear by the benefits of coconut oil, while others find that it only makes things worse. In any case, there’s evidence that coconut oil can reduce skin inflammation and enhance barrier function, both of which are beneficial for eczema (22).
  • Aloe vera: this popular plant is proposed to have antibacterial, wound healing, and immunity-modulating properties (23). However, there’s a lack of evidence for its benefits specifically in eczema.

How To Apply CBD Topicals for Eczema

You can apply a topical CBD product directly to the area of skin affected by eczema. It’s best to clean and dry the area first and then massage the product into your skin as you would with most regular topicals.

You can start with a small amount and see if that provides you with some relief. If that’s not enough, you can always apply more later.

Can Topical CBD Cause a Failed Drug Test for THC?

It’s highly unlikely that a topical CBD product will show up as a positive drug test for THC. Not only do CBD products contain very small THC amounts (less than 0.3%) but topically applied CBD has a hard time reaching the bloodstream. 

Can You Apply CBD Oil to Eczema?

Yes, you can apply standard CBD oil to eczema. Having said that, you’ll probably have better results from using a dedicated topical product since CBD oil tinctures are designed to be taken sublingually (under the tongue).

Topicals vs. Other CBD Products

Topical CBD products differ from CBD oil, capsules, and edibles in several important ways. For one, they’re applied to the skin instead of taken orally. Furthermore, their effects are only felt where you apply them, instead of the whole body. 

One advantage of topical products is that the CBD is unlikely to absorb deep enough to reach the bloodstream, which reduces your chances of side effects. The effects of topical CBD last for at least a few hours.

References

  1. Russo, Ethan B. “Taming THC: potential cannabis synergy and phytocannabinoid‐terpenoid entourage effects.” British journal of pharmacology 163.7 (2011): 1344-1364.
  2. Pamplona, Fabricio A., Lorenzo Rolim da Silva, and Ana Carolina Coan. “Potential clinical benefits of CBD-rich cannabis extracts over purified CBD in treatment-resistant epilepsy: observational data meta-analysis.” Frontiers in neurology 9 (2018): 759.
  3. https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
  4. Laughter, M. R., et al. “The global burden of atopic dermatitis: lessons from the Global Burden of Disease Study 1990–2017.” British Journal of Dermatology 184.2 (2021): 304-309.
  5. Palmieri, B., C. Laurino, and M. Vadalà. “A therapeutic effect of cbd-enriched ointment in inflammatory skin diseases and cutaneous scars.” Clin Ter 170.2 (2019): e93-e99.
  6. Sales, Amanda J., et al. “Cannabidiol induces rapid and sustained antidepressant-like effects through increased BDNF signaling and synaptogenesis in the prefrontal cortex.” Molecular neurobiology 56.2 (2019): 1070-1081.
  7. Blessing, Esther M., et al. “Cannabidiol as a potential treatment for anxiety disorders.” Neurotherapeutics 12.4 (2015): 825-836.
  8. Shannon, Scott, et al. “Cannabidiol in anxiety and sleep: a large case series.” The Permanente Journal 23 (2019).
  9. Schonmann, Yochai, et al. “Atopic eczema in adulthood and risk of depression and anxiety: a population-based cohort study.” The Journal of Allergy and Clinical Immunology: In Practice 8.1 (2020): 248-257.
  10. Callaway, James, et al. “Efficacy of dietary hempseed oil in patients with atopic dermatitis.” Journal of Dermatological Treatment 16.2 (2005): 87-94.
  11. Trusler, Alexandra R., et al. “The endocannabinoid system and its role in eczematous dermatoses.” Dermatitis 28.1 (2017): 22-32.
  12. Del Río, Carmen, et al. “The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders.” Biochemical pharmacology 157 (2018): 122-133.
  13. Leweke, F. M., et al. “Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia.” Translational psychiatry 2.3 (2012): e94-e94.
  14. Schlosburg, Joel E., et al. “Endocannabinoid modulation of scratching response in an acute allergenic model: a new prospective neural therapeutic target for pruritus.” Journal of Pharmacology and Experimental Therapeutics 329.1 (2009): 314-323.
  15. Sheriff, Tabrez, et al. “The potential role of cannabinoids in dermatology.” Journal of Dermatological Treatment 31.8 (2020): 839-845.
  16. Pandey, Rupal, et al. “Endocannabinoids and immune regulation.” Pharmacological research 60.2 (2009): 85-92.
  17. Teo, Cheryl Wei Ling, et al. “Vitamin E in Atopic Dermatitis: From Preclinical to Clinical Studies.” Dermatology 237.4 (2021): 553-564.
  18. Fowler, Joseph F., et al. “Colloidal oatmeal formulations as adjunct treatments in atopic dermatitis.” J Drugs Dermatol 11.7 (2012): 804-807.
  19. Hon, Kam Lun, et al. “Emollient treatment of atopic dermatitis: latest evidence and clinical considerations.” Drugs in context 7 (2018).
  20. Alangari, Abdullah A., et al. “Honey is potentially effective in the treatment of atopic dermatitis: Clinical and mechanistic studies.” Immunity, Inflammation and Disease 5.2 (2017): 190-199.
  21. Wallengren, Joanna. “Tea tree oil attenuates experimental contact dermatitis.” Archives of dermatological research 303.5 (2011): 333-338.
  22. Varma, Sandeep R., et al. “In vitro anti-inflammatory and skin protective properties of Virgin coconut oil.” Journal of traditional and complementary medicine 9.1 (2019): 5-14.
  23. Radha, Maharjan H., and Nampoothiri P. Laxmipriya. “Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review.” Journal of traditional and complementary medicine 5.1 (2015): 21-26.

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